hkcmgc
中文 | English
HEALTH MANAGEMENT
Cardiovascular Disease Assessment
Early Assessment of Genetic
Risk, Take Proactive Care of
Your Heart
Early intervention helps with your future family planning
Knowing Your Individual Risk for Cardiovascular Disease
Covers the most common inherited cardiac conditions such as cardiomyopathies and arrhythmias
Comprehensive
Screening
Identifies 30 genes
associated with 15
inherited cardiac conditions
Cardiovascular Disease Assessment
Cardiovascular disease is a leading cause of mortality and morbidity worldwide; it has been the 3rd leading cause of death in HK since the 1960s. Due to its severity and often asymptomatic nature, spotting genetic heart disease early on is imperative to its effective prevention and treatment in the future. Cardiovascular disease does not only affect the elderly, we have all heard of Sudden Cardiac Death(SCD), which can also occur in young(ages below 40) and healthy people. This makes getting a test even more crucial for you and your family’s peace of mind.

Hong Kong Cytogenetics and Medical Genetics Centre Limited provides comprehensive genetic testing, allowing you/your doctor to spot any predisposition to inherited heart disease early on.
30
genes
15
inherited cardiac conditions
30genes, 15inherited cardiac conditions
Early Assessment of Genetic Heart Disease Testing
One of the main reasons heart disease can affect anyone, is that in many cases, heart conditions are found to be hereditary, where genetics plays a direct role. Most people are only concerned with the environmental factors that can affect their heart, without considering their genetic factors which can only be determined through screening.

The good news is, here in Hong Kong at the HKCMGC facilities, we are able to test for these genetic components and give you a comprehensive assessment of your risk with the latest genetic sequencing technology. This lets you have the utmost confidence in your results, and our experts.
What Genetics Means To You?
By receiving our comprehensive heart disease screening you will understand not only where you stand in terms of genetic risk, but also where your family stands. Chances are if you have a genetic risk factor, your relatives will as well.

A cardiovascular disease genetic test is more than just assessing your genes; it is your health and your future. By catching it early, your doctors are able to identify those with a predisposition for inherited heart disease and can initiate early intervention strategies, which could be a potential lifesaver.
Disease Type
Cardiomyopathies
(5 Items)
Hypertrophic Cardiomyopathy
Dilated Cardiomyopathy
Arrhythmogenic Right Ventricular Cardiomyopathy
Non-Compaction Cardiomyopathy
Restrictive Cardiomyopathy
Arrhythmias
(4 Items)
Long QT Syndrome
Brugada Syndrome
Short QT Syndrome
Familial Atrial Fibrillation
Aortopathies
(4 Items)
Marfan Syndrome
Loeys-Dietz Syndrome
Familial Aortic Aneurysm
Aortic Valve Disease
Other Cardiac Conditions
(2 Items)
Structural Heart Disease
Familial Hypercholesterolemia
Limitations of current SoCs
Techniques
Types
Disadvantage
Electrocardiography (ECG)
Stress ECG
Resting ECG
Can not reflect the situation of entire heart
Only record impulses of a few minutes
Diagnostic Imaging
Ultrasound
X-ray
MRI
CT
PET Scan
Lack of penetration
Radiation exposure could be harmful
Can induce claustrophobia
Extremely complex and expensive
High doses of radiation
The tracer may cause allergic reaction
* Whilst genetic testing provides early screening for proactive care, it does not replace current standard of care (SoC). The results should be used in conjunction with the diagnostic imaging in accordance with appropriate patient management procedures
Who should consider the service
Anyone who wishes to assess their cardiac risk
Individuals with a family history of cardiovascular disease (5 times higher risk of developing cardiovascular disease)
Individuals who have had a family member that died suddenly with no obvious cause or explanation
Fainting during exercise, excitement, or upon sudden shock or surprise
Consistent or unusual chest pain and/or shortness of breath during exercise
誰該考慮此服務
Service Features
Comprehensive coverage
Identifies 30 common genes associated with
15 inherited cardiac conditions
High Precision
Next Generation Sequencing (NGS) Technology,
with an average depth of > 300X
Reliable Data and Professional Insights
Our team of scientific experts analyzes your genes
based on reliable databases to report reliable
genetic data and identify the DNA variations that
are associated with related conditions
Simple
Only 3-5 ml of blood is required

As a one stop service, our centre
is equipped with the expertise of cytogenetics
and molecular genetics

Procedures
電話預約
Make an appointment with our clinic
抵達中心後,我們會評估及記錄您的家族
史和疑慮。抽血前,您需要簽署同意書
At the clinic, we will record and assess your family history and your concerns. You will be asked to
give consent before our phlebotomist collects
your blood
血液樣本會被送到我們的化驗所,並用以
提取高純度的DNA
The blood specimen is sent to the laboratory. DNA is extracted, and enriched using Next-Generation Sequencing technology to prepare for genetic analysis
採用NGS次世代定序技術,進行基因序列 並利用生物資訊進一步分析處理基因數據
Bioinformatics analytic techniques are used to
process your genetic data, allowing us to focus on the regions of interest
22個工作天內完成遺傳性心臟疾病風險
評估報告
Report will be ready within 22 working days, containing your specific genetic variants related to inherited cardiac conditions, if any, and interpretation